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Project

BCG+MM Trial: Adding mitomycin to BCG as adjuvant intravesical therapy for high-risk, nonâ muscle-invasive bladder cancer: a 2-stage, randomised phase 3 trial.

Funder: National Health and Medical Research Council

Funding period
AUD 1.6 M
USD 1.1 M
Funding amount
Abstract
Non-muscle invasive bladder cancer is common, causes substantial suffering and requires radical removal or irradiation of the bladder within 5 years in over 30% of people with high risk tumours despite best current treatment. Preliminary studies show exciting results from adding mitomycin (a chemotherapy drug) to best current treatment with BCG (an immunotherapy). This large randomized trial will determine the effects of adding mitomycin on cure rates, survival, side effects and quality of life.
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System

Categories
  • FOR (ANZSRC)

    1103 Clinical Sciences

  • FOR (ANZSRC)

    1112 Oncology and Carcinogenesis

  • RCDC

    Cancer

  • RCDC

    Clinical Research

  • RCDC

    Clinical Trials and Supportive Activities

  • RCDC

    Urologic Diseases

  • HRCS HC

    Cancer

  • HRCS RAC

    6.1 Pharmaceuticals

  • Health Research Areas

    Clinical

  • Broad Research Areas

    Clinical Medicine and Science