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Project

Development of a utility weighting function for the Bladder Utility Symptom Scale (BUSS-U)

Funder: Canadian Cancer Society

Funding period
CAD 300 K
USD 246 K
Funding amount
Abstract
Many people with bladder cancer must make choices about treatment. Treatments can cure the cancer, but have side effects that affect one�s quality of life. For example, surgery removes the bladder and the cancer, but an external urine bag is needed to replace the bladder. A person�s preference for trade-offs between quality of life and cancer control is important during the decision-making process. �Utility� is a way to measure quality of life that takes into account what patients prefer. Available questionnaires used to measure utility do not include symptoms important to bladder cancer patients, such as urinary and bowel problems. This study will develop a quality of life questionnaire to measure utility for patients with bladder cancer. In a previous study, Dr Krahn�s group developed a questionnaire to measure quality of life and utility in patients with prostate cancer. Patients can answer 10 multiple-choice questions and receive scores that describe their symptoms and their overall quality of life as measured by utility. This information is useful to patients, doctors and researchers who must make decisions about treatment. Recently, these researchers interviewed bladder cancer patients and medical experts to find out what is important to the quality of life of bladder cancer patients. Using this information, they developed a 10 question quality of life questionnaire for bladder cancer patients that describes symptoms and is applicable to all bladder cancer patients, but does not yet provide a quality of life utility score.The goal of this study is to develop a scoring system that will calculate utility scores from the new bladder cancer questionnaire. Patients will be able to answer 10 multiple-choice questions and get a score that includes a measure of quality of life that considers preferences for care. The researchers will interview 200 bladder cancer patients and 200 community members. Patients will be asked about their preferences for different descriptions of health, such as tiredness, urinary problems, mood and pain. The researchers will use this information to determine utility weights, or numerical values, that reflect how people rate different descriptions of health and quality of life. The utility weights will be used to score the bladder cancer questionnaire. The final value will be a utility score that will describe patients� overall quality of life.Patient preference (those aspects of health and quality of life patients prefer and think are important) is an important consideration when patients, doctors and others make decisions about treatment for bladder cancer. Currently, there is no method to measure patient preferences in bladder cancer. This study will capture information about how patients experience bladder cancer. The questionnaire to be developed will allow for more patient-centred care and help researchers and policy-makers to consider patient preferences. This study and questionnaire will increase awareness of the importance of patient preference and quality of life in bladder cancer and its treatment. Finally, this study will create a tool that can be used by researchers around the world to help determine the effectiveness of treatments for bladder cancer that take into account patient preference.
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System

Categories
  • FOR (ANZSRC)

    1112 Oncology and Carcinogenesis

  • FOR (ANZSRC)

    1117 Public Health and Health Services

  • FOR (ANZSRC)

    1402 Applied Economics

  • RCDC

    Aging

  • RCDC

    Behavioral and Social Science

  • RCDC

    Cancer

  • RCDC

    Clinical Research

  • RCDC

    Urologic Diseases

  • HRCS HC

    Cancer

  • HRCS RAC

    7.1 Individual care needs

  • HRCS RAC

    8.4 Research design and methodologies

  • Health Research Areas

    Health services & systems

  • Broad Research Areas

    Health Services Research